KIN 275 Lecture Notes - Lecture 3: Wiggers Diagram, Cardiac Output, Hemodynamics

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Cardiac output (q): total volume of blood pumped per minute. Q = hr x sv: rhr ~70 bpm, standing sv ~70 ml/beat = 4,900 ml/min, use l/min (4. 9 l/min) - reasonable q at rest. Wiggers diagram: atrial and ventricle pressure waves changes. Arteries - carry blood away: very high pressure, oxygenated blood. Veins: low pressure, carry deoxygenated blood, venous circulation. Upright posture makes venous return to heart more difficult: three mechanisms assist venous return. Thursday, april 14, y: blood pressure gradient. Drop as go to smaller vessels: general hemodynamics. Baroreceptors: sensitive to arterial pressure changes, afferent signals to brain to change pressure if required. Vasodilation or constriction: adjust arterial pressure back to normal. Resistance: force that opposes flow, provided by physical properties of vessels, radius is most important factor (drinking through large straw or tiny straw) Blood flow where needed most, regions of metabolism > increased blood flow: blood flow changes after eating or in heat.

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