PHAR 441 Lecture Notes - Lecture 1: Hypogonadotropic Hypogonadism, Human Chorionic Gonadotropin, Gonadotropin-Releasing Hormone Receptor
8 Sep 2016
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Document Summary
Drugs and the control of sex hormone production. Adrenal medulla hormones, thyroid hormones, pineal gland hormones. Fsh & work on to the activated by peptide kisspeptin released by the hypothalamus (arcuate nucleus) anterior pituitary. Lh: are released from the anterior pituitary and different cells. They also create negative feedback hypothalamus to inhibit the release of gnrh. Fertilized ovum, then by the placenta in pregnancy. Glycosylation not identical among the different hormones, which causes there to be. Stimulates the growth of the developing ovarian follicles during the first half of the menstrual cycle, and promotes the synthesis of estrogen (lh is also required) Shorter 30 min because a sulfated n- acetylgalactosamine is attached to lh. Induces ovulation, and stimulates progesterone and estrogen synthesis by the corpus luteum (formed form the remaining cells of the ruptures follicle) during the second half of the menstrual cycle. Acts to maintain the corpus luteum when ovum is fertilized.
