PHAR 451 Lecture Notes - Lecture 2: Prospective Cohort Study, Bone Density, Iron-Deficiency Anemia
21 Sep 2016
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Note: lh has a dip before the rise, then 12 hours after the peak there is ovulation. Used by or obviously visible to the women. To introduce use of long acting reversible contraception (larc) by removing financial and knowledge barriers. Study design prospective cohort study of 10,000 women 14-45 years old. Continuation rate (2 yr): non-larc 41% vs. larc 77% Pregnancy rate: non-larc were 20 times more likely to become pregnant than larc. Ease of administration, fairly low incidence side effects. Low pregnancy rate (0. 3% perfect use, 8% typical use) Smoker of > 35 years age (>15 cigarettes/day) Hypertension (sbp > 160 mm hg or dbp > 100 mm hg) Complicated heart disease: ischemic, atrial fibrillation, valvular conditions. Migrained with aura at any age serious se. St. john"s wort: induces ee-norethindrone metabolism consistent with increase. Women taking oc pills should be counselled to expect breakthough bleeding and should consider adding barrier method of contraception when consuming st. john"s wort.
