PHAR 451 Lecture Notes - Lecture 17: Clopidogrel, Ramipril, Antithrombotic
10 Dec 2016
School
Department
Course
Professor
Document Summary
Design and rationalize using evidence, a stroke prevention regimen in each of the following clinical scenarios: Statin (simva, prava, atorva) in high risk patients: especially in those with cad, regardless of baseline cholesterol levels. 6 trials, asa 50-500 mg/day, mean follow up = 6. 4 yrs. Prevents overall cv events in low-risk males & females. Your patient has a 1 in ~2000 chance of benefit for every year they take aspirin. Your patient has a 1 in ~2700 chance of benefit for every year they take aspirin. Your patient has a 1 in ~750 chance of benefit for every year they take aspirin. Your patient has a 1 in ~5000 chance of harm for every year they take aspirin. Your patient has a 1 in ~2200 chance of harm for every year they take aspirin. Dm2, abpi <0. 99 but no symptomatic cv disease. Do(cid:374)"t gi(cid:448)e to dia(cid:271)eti(cid:272)s no benefit. Chd death + mi/stroke + amputation hr 0. 98 [0. 76-1. 26]
