PHAR 454 Lecture Notes - Lecture 10: Highly Questionable, Alteratie, Homeopathy

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Dr. m wessel studied (cid:862)e(cid:454)(cid:272)essi(cid:448)el(cid:455) fuss(cid:455) (cid:272)hildre(cid:374)(cid:863) a(cid:374)d defi(cid:374)ed (cid:272)oli(cid:272) as: >3 hrs/day, for >3 days/week, for >3 weeks (cid:862)diag(cid:374)osti(cid:272) rule of (cid:1007)"s(cid:863) = wessel"s criteria term used in clinical studies. Self-limited, intermittent, unexplained excess crying clusters in the afternoon and evening. Affects 15-20% of babies onset after 2-4 weeks of age. 50% of cases end at 3 months, can persist to 4 months, but rarely to 6 months. Self-limited, no long-term sequelae, no increased risk of future colicky babies. Causes that have been refuted/cannot be proven: inadequacy of care, excess stimulation, parental anxiety/stress, immature cns (premature baby), temperament, gi tract inflammation. Theory that has been most favored/studied: gi-related etiology: gi intolerances producing discomfort (ex. Only in 5% of cases there is an underlying pathology. Must rule out abnormal physical findings and gi disorders (if ~4 months, consider gerd) Duration, when it started, any changes around the time it started.

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