PHRM 111 Lecture Notes - Lecture 14: Dry Eye Syndrome, Allergic Conjunctivitis, Contact Lens
Document Summary
Giant papillary conjunctivitis (gpc) clear white discharge. Vkc onset in childhood ; chronic course with acute exacerbations in spring and summer. Akc genetic predisposition, environmental allergens; chronic course; later onset than vkc. Gpc contact lens wear, irritation from sutures. Seasonal : pollens (grass pollen is the most common cause of ocular symptoms) Cool compresses x 20 minutes (up to 6 times daily) may be soothing. Preservative-free may be more soothing: ophthalmic ah + decongestants (otc) Contraindicated in patients predisposed to angle-closure glaucoma: ophthalmic mast cell stabilizers (mcs) Stabilize mast cells and prevent release of inflammatory mediators. Generally for recurrent/persistent symptoms (sac or pac) Symptomatic relief in 3 days for some, but often much longer in most patients (start. Patients often perceive mcs as less effective than ah + mcs (just faster onset) Sodium cromoglycate >4 yo; lodoxamide 2 yo: ophthalmic ah + mcs ( 1st line )
