PHRM 211 Lecture Notes - Lecture 28: Multiple Sclerosis, Grey Matter, Neurodegeneration
Document Summary
Educate on existing and new ms drugs on the horizon. Identify adverse drug reactions, drug interactions, and contraindications of ms medications with comorbid conditions and medications. Patient advocacy due to cost and access of medications (up to ,000/year) Chronic, inflammatory , and neurodegenerative disorder of the brain, spinal cord, and optic nerves. Myelin is an insulating layer that forms around nerves, including those in the brain and spinal cord. Allows for electrical impulses to transmit quickly and efficiently though nerve cells. Demyelination results in the interruption of electrical impulses clinical symptoms. Areas where demyelination occurs is known as lesions or plaques. Cross-section of the brain gray matter (exterior) and white matter (interior) Recall: the brain is made up of about 100 billion nerve cells, known as neurons. Cell membrane (over the dendrite and cell body) gives gray matter its gray colour and the myelin sheath (over the axon) gives the white matter its colour.
