PSYC 101 Lecture Notes - Lecture 8: Excitatory Postsynaptic Potential, Inhibitory Postsynaptic Potential, Neurotransmitter Receptor
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PSYC 101 Full Course Notes
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Hodgin and huxley (1939): discovered the resting potential in the giant axon of the giant squid: 100x larger than human axons they were able to t one of their electrode in the squid they could record the -50mv. Uid released from heart of one frog slowed down heart of second frog must be chemical transmission. He dissected the still beating hearts from two frogs, and put them into petri dishes. Chemical transmission once the action potential reaches the axon terminal synaptic terminal has vesicles that are waiting for a signal. Getting rid of the neurotransmitters: enzymes: metabolizes the neurotransmitters, transporter molecule: push it out through the vesicles, and reuptake it through the transporter molecule, receptor molecules: when they get stimulated, they will shut the neuron down. Post synaptic e ects autoreceptor mechanism neurotransmitter binds to appropriate receptor on the dendrite, results in change of membrane potential. Esps and isps excitatory post-synaptic potential inhibitory post-synaptic potential.
