PSYC 304 Lecture Notes - Lecture 4: Inhibitory Postsynaptic Potential, Resting Potential, Axon Hillock
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*midterm will only include up to1st half of chapter 5 from textbook. 3) energy-consuming process (dephosphorylation) what affects resting membrane potential? (inputs from other cells) Epsps + ipsps summate -> reaches/exceeds level of threshold -> ap (massive momentary reversal to positive voltage then goes back down) Epsps + ipsps sum spatially (location-wise of cell) as well as temporally. Psps are always overlapping and interacting temporal summation: single input from 1 other neuron; not static entity; multiple psps in rapid succession to produce a larger sum of psp. Ap generation and conduction both results from voltage-activated ion channels ionic basis of aps. Rising phase: voltage-activated na+ channels open after threshold is crossed -> ap, peak of ap: na+ channels close & voltage-gated k+ channels open = k+ slowly leaves = ~-30 mv; k+ still open during peak. 5) too many k+ leaves cell = brief hyperpolarization phase refractory state.
