BIOL 1010U Lecture 11: CH11_Cell Division and Cell Cycle WF Notes

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Definition: one of the fundamental principles of biology. Key roles: cells reproduce via cell division: reproduction. New copy may be identical or have mutations exact copies of parental chromosomes. Prokaryotes (e. g. bacteria) and other single- celled organisms (amoebae, paramecia etc. ) Produces daughter cells (gametes) with half the number of chromosomes compared to parent cell. Most bacteria one circular chromosome, highly folded and coiled. Two important regions on dna: origin of replication, terminus of replication. Two origins (attached to plasma membrane) move apart. Pinching in of plasma synthesis of new cell wall materials. One gene, ftsz, encodes for a protein that forms the ring at site where cell constricts and new cell wall will form between the daughter cells. Ftsz is present in many diverse bacteria and archaea: suggests it plays a fundamental role in prokaryotic cell division, the protein it encodes appears evolutionarily related to tubulin. Ftsz is a gene that controls bacterial cell division.

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