HLSC 2110U Lecture Notes - Lecture 11: Nuclear Material, Drug Resistance, Plasmid
26 Feb 2019
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Document Summary
Dna copies and goes on the daughter cells. From dna to protein: the central dogma of molecular biology. Thymine is not in rna, but is replaced with uracil. Base pairs are connected by hydrogen bonds. 5" phosphate is attached other phosphate attached by 3". Separation of the two dna strands in the double helix: Guanine and cytosine is stronger than adenine and thymine since they have three hydrogen bonds. By heating and changing the ph (to acidic) Can come back together when there is normal conditions (recombination/annealing) A form same form as b but it is dried out, same confirmation as b form. Expressions are not clear, most predominant is the b form, they also have regulatory functions. Eukaryotic mitochondria mitochondrial dna, circular dna molecules. Bacteria plasmid (free portion of dna carries genetic info) In adverse environments bacteria in medium such as antibiotics, plasmids produce an antagonizing material and antagonizes the antibiotics which causes drug resistance.
