ANP 1105 Lecture 6: Topic 4 (Blood) Notes

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Rbcs: most dense cellular component, 45% of blood. Wbcs and platelets: medium density, <1% of blood. Original stem cell for all formed elements: hemocytoblast. Color is scarlet (when o2 rich) to dark red (o2 poor) More dense and viscous than water ph: 7. 35 7. 45: too low: acidosis, too high: alkalosis. Temperature: around 38oc, can be cooler in extremities. Distribution: oxygen and nutrients to tissues, metabolic wastes to kidneys and lungs, hormones. Protection: prevents blood loss, heals open sources for infection (platelets, plasma proteins, blood clotting, immune system (antibodies, complement, wbc"s) Biconcave discs collapsed area is where the nucleus was before being ejected: collapsed shape increases surface area and allows more gases to be transported. Bags of hemoglobin but has other proteins too: spectrin: maintains cell shape, protein that allows the cell to regain its shape after squeezing through small areas (ex. Transports ox from lungs to tissues, transports 20% of co2 back to lungs.

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