ANP 1105 Lecture Notes - Lecture 2: Fluid Mosaic Model, Lipid Bilayer, Tight Junction

• School: University of Ottawa
• Department: Anatomy and Physiology
• Course: ANP 1105
• Professor: Jackie Carnegie

Document Summary

Topic 2 notes- cellular physiology of nerve and muscle. Basic structure according to uid mosaic model. Phospholipid bilayer: molecule with a polar, hydrophilic head with a phosphate group attached, with two fatty acid chains that are hydrophobic. Fluid mosaic model: composed of many components that are not set in one place. Pieces tend to oat in the bilayer and can move around forming a mosaic. Integral proteins: span the plasma membrane (pm), span hydrophobic and hydrophilic regions and act as channels or carriers. Peripheral proteins: attached to integral proteins, usually on inside of pm, can be enzymes, they"re involved in attachment functions and shape changes. Cytoskeleton: anchors to pm and can also interact with receptors. Glycocalyx: ensemble of carbohydrates atta he"d to lipids and proteins on the extra cellular face sugar coating on pm. Cholesterol: reduces general membrane uidity and stabilizes it structure, too much cholesterol causes membranes to lose exibility.