BIO 1140 Lecture Notes - Lecture 6: Phosphatidylserine, Flippase, Membrane Transport
25 Aug 2017
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Mitochondria part 2 : apoptosis/ cell communication: :: what are ways/tyoes/rxns in which cells interact and communicate with each other to accomplish a task/job. !1: direct signalling (gap junctions, sending a molecule from one cell to another, neoronal signalling. Atp and translocates phosphatidylserine to the outer lea et: scrambalses : not an atpase; does not need energy/atp. !6 once u initiate that cascade of events that leads to the death of the cell. We r going to activate an apoptotic protein that favors apoptotic process and this is on a leash by phoshorolated. when u trigger the intrinsic pathway u take of the leash this protein goes and kills the cell. Christae changes the arrangement; that hole is called a permeability transition pore (ptp). It punches the outer membrane of mitochondria and it allows the protein cytochrome c that lives btw 2 membranes and it is able to exit mitochondria and going to trigger caspase cascade.
