BPS 2110 Lecture 20: bps2110-lecture 20
3 Dec 2016
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Document Summary
Tablets: solid dosage forms prepared by compression or molding and containing: Non-medicinal ingredient: many shapes: round, oblong, oval, triangular, square, rectangular, hexagonal, heart, etc . Key consideration: exposure of the drug substance to the dissolution process may involve a few steps. Types of tablets: compressed tablets, film-coated tablets, enteric-coated tablets, buccal and sublingual tablets, chewable tablets. Tablets qualities: accurate & uniform weight, homogeneity, absence of incompatibilities, stability & hardness, ease of disintegration, reasonable size and shape, pleasing appearance, ease of manufacturing, economy of production. Tablets characteristics: tablet hardness, tablet thickness, tablet weight, content uniformity, disintegration. Excipients are inert substances used to give a preparation a suitable form or consistency. Hard enough to resist breaking during normal handling. No more than 1% weight loss during friability test: disintegration, six tablets are assayed, tubes lowered & raised in immersion fluid at 29 30 cycles per minutes at.
