BPS 2110 Lecture Notes - Lecture 5: Phenyl Group, Teratology, Penicillium

24 views6 pages

Document Summary

Prior to 2000, estimated that 60% of all new antibiotics have a natural product origin. Development of penicillin showed people how valuable antibiotics could be. Wwi: many people died from infections, showed the need for more antibiotics. By the late 1970s so many antibiotics were available that it was no longer pro table to pursue new antibiotics. By the 1990s, the rst antibiotic resistant bacteria appeared. 50% of all anticancer drugs have a natural product origin. Many cns active drugs are synthetic but based upon natural products. Ethnopharmacology: plants to treat infections, stomach/intestinal ailments, pain, mental disorders, reproductive issues. Bioavailable: represents the amount of the drug that gets to the bloodstream. Allows for systemic distribution through the bloodstream (still dif cult to get to the brain due to blood brain barrier) We can control through chemical modi cation how fast it"s absorbed, how fast it"s broken down, how long it stays in the blood stream, etc.

Get access

Grade+
$40 USD/m
Billed monthly
Grade+
Homework Help
Study Guides
Textbook Solutions
Class Notes
Textbook Notes
Booster Class
10 Verified Answers
Class+
$30 USD/m
Billed monthly
Class+
Homework Help
Study Guides
Textbook Solutions
Class Notes
Textbook Notes
Booster Class
7 Verified Answers

Related Documents