BPS 2110 Lecture Notes - Lecture 8: Bone Marrow Suppression, Beta-Lactam, Chronic Myelogenous Leukemia
7 Nov 2017
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Possibly to focus attention away from the viet nam war or to leave a cure for cancer as his legacy. Nixon as president of the us declared war on cancer in 1970 with goal of conquering cancer by the end of the century. Asked us congress to authorize funding of this project via the us national cancer institute (nci) Chemists, biochemists, molecular biologists, and mds at many universities responded with many projects. There were some natural compounds that already seemed to be working so they gured that they just had to keep screening compounds and that they would be able to nd a cure. From plants: madagascar periwinkle: vincristine and vinblastine for childhood leukaemia, north american may apple: etoposide for small cell lung cancer. From micro-organisms: sewer ef uent, triest,iitaly micro-organism, adriamycin (doxorubicin) Unlikely to be conceived as a potential anticancer compound by a medicinal chemist.
