PSY 2301 Lecture 7: Neural Integration
9 Feb 2017
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Where the ions are located when the cell is at rest: negative inside, positive outside. Maintaining resting potential: key facts: inside the cell. K+ accumulates inside to balance the negative charge. Concentration gradient prevents k+ from entering indeed some leave this helps maintain the potential. Overall more k+ inside than outside: key facts: outside the cell. Gates keep na+ (the gates are usually closed) Na+ that leaks in is transported out by sodium-potassium pumps (3 na+ out for every 2 k+ in) Equilibrium of cl- matches the resting potential so cl- doesn"t contribute to the potential. Graded potentials: hyperpolarization: causes efflux of k+ or influx of cl- Can be blocked by blocking k+ channels with tea: depolarization: causes influx of na+ Can be blocked by blocking na+ channels with ttx. They usually take place on the cell body (soma) or at dendrites. They are electrical (they represent small local changes in membrane potential)
