ANT214H5 Lecture Notes - Lecture 5: Insulin Resistance, Human Microbiome Project, Commensalism
Document Summary
The agr icu ltur al revo lu tio n: he alth and the micr ob io me. Extra food trade store, feed to animals: development of non-subsistence related roles in community (i. e. , artisans, warriors, healers) No seasonal variation in access to food: no growth-related pathological conditions (e. g. , short adult stature) Injuries and medical problems easier to deal with: wounded and sick don"t need to be moved i. e. they heal better. Stored food: attracts vermin (i. e. , rats who carry disease) Zoonoses (infectious diseases caused by bacteria, viruses, and parasites spread between animals) Heavy workload: high rate of degenerative and joint diseases. Staple crops: high carbohydrates poor dental health. Ecological community of commensal, symbiotic and pathogenic microorganisms that share our body. Genetic composition of gut microflora unique and stable through time. Dysbiotic microbiome = diseases: obesity, diabetes, malnutrition, cancer, ibs. Physical and social environment change: human microbial environment changes during each transition.
