BIO152H5 Lecture Notes - Lecture 7: Zygosity, Fundamental Theorem Of Arithmetic, Wild Type

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Chromosome theory of inheritance: mendelian genes have specific loci along chromosomes that undergo segregation and independent assortment. Fruit fly (drosophila melongaster: p: all flies have red eyes. Conclusion: red eye color is dominant to white: f1: female flies have red eyes, male flies have white eyes. Sex-linked inheritance: a trait determined by genes on the sex chromosome is said to be sex linked. In ovaries, barr body chromosomes are re-activated in the cells that give rise to eggs, resulting in every female gamete having an active x. Mutant alleles are recessive to wild-type and are not sex-linked: most offspring had a parental phenotype suggesting the body color and wing size are linked on the same chromosome and are thus inherited together. Abnormal chromosome number (nondisjunction: aneuploidy: an abnormal number of chromosomes, monosomic: a missing chromosome, trisomic: an extra chromosome, polyploidy: more than 2n chromosomes in all somatic cells.

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