BIO206H5 Lecture Notes - Lecture 16: Okazaki Fragments, Helicase, Dna Gyrase
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Bio206 lecture 16 dna replication: the rules. Direct source of energy for polymerization would be missing if dna strands were synthesized in 3" to 5" direction important part of dna complex improves the replication. The replication bubble is being stabilized by ssbs constantly single stranded dna strand exposed will be in complex with single stranded binding proteins. Other components that are a part of this are clamp loader with tauc linker region. This is a complicated protein complex that allows for loading and unloading of clamp protein. Clamp protein is really important holds dna polymerase on dna stabilizes interaction of dnapiii and single stranded dna. The lagging strand is a dynamic relation between clamp and clamp loader clamp is being loaded on and taken off repeatedly at different times. There are segments of dna where small portions of double stranded. Dna (red and white on sb video) migrated down the chain to a specific location building up the replisome.
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