BIO310H5 Lecture Notes - Lecture 4: Endoplasmic Reticulum, Electrical Synapse, Sodium Channel
Document Summary
Slide 3: neuron to neuron or muscle to neuron. First neuron is connected to receptors: the connection between neurons is through synapses. If post-synaptic neuron thinks that the signal is worth it, then it will pass it on. In pre-synaptic neurons, it is rich with: presynaptic vesicles are filled with neurotransmitters which are synthesized at synaptic knob, mitochondria because it needs a lot of energy, endoplasmic reticulum because there is a lot of synthesis. Slide 5: electrical synapse occurs between gap junctions and are direct, direct communication, they do(cid:374)"t i(cid:374)(cid:448)ol(cid:448)e (cid:374)eurotra(cid:374)s(cid:373)itters. Sodium ions can pass: the charge will be transported through the adjacent cells. Slide 9: as soon as the action potential is formed, it has to be propagated until it reaches the end of the axon. Slide 11: as far as we see vesicles, we are talking about pre-synaptic, we are looking at membrane bound proteins.
