BIO315H5 Lecture Notes - Lecture 3: Diglyceride, Cytosol, Conformational Change
Document Summary
Chapter 15 lecture #3 january 9th, 2017. Positive feedback causes all or none responses. Negative feedback, even if the signal continues, the response can be turned off because the cell has stopped responding. Adaptation is the process if you have prolonged exposure to that signal, the response to it reduces: allows the cell to respond to a wide range of signal concentrations, cell mostly respond to changes in the concentration. Receptor sequestration after the receptor has been activated the signaling molecule and receptor gets internalized, so even if you do have the signal molecule available there is no receptor to bind to. Receptor down-regulation the internalized receptor and signal molecule is digested. Receptor inactivation the receptor is still available at the plasma membrane but is inactive nonetheless. Production of inhibitory protein the inhibitory protein prevents the coupling of the activate receptor to the intracellular signaling protein.
