FSC239Y5 Lecture Notes - Lecture 7: Vehicle, Sexual Assault, Somnolence
Document Summary
Forensic toxicology is the study of the adverse effects of drugs and poisons on the human body and the application if this information to matters of the law. Could the drug produce impairment of the individual"s psychomotor capabilities: sexual assault investigation. Purpose: to determine the presence/absence and quantity of drugs, alcohol, and or poisons in the specimen. Blood: drug in body at the time of collection of death. Serum/plasma: obtained from anti-mortem blood drug in body at time of collection. Liver: post-mortem: drug in body at the time of death: qualitatively. Urine: anti-mortem or post-mortem indicates prior use qualitative as drug concentrations in urine are not generally interpretable (exception: alcohol, ghb) Mostly post-mortem: indicates ingestion but amount of drug in blood not known. Drug paraptiematia: useful to guide investigation does not indicate whether drug administered. Screening: qualitative identification of drugs or drug classes gas chromatography/mass spectrometry immunoassay. Targeted/ confirmation/ quantitation determination and contamination of rug concentration liquid chromatography _- ms?ms.
