PSY290H5 Lecture Notes - Lecture 5: Otto Loewi, Postsynaptic Density, Choline
Document Summary
His most profound research came to him while he was dreaming. If you actually separate an organ from an animal, you could trigger a stimulation of that organ and count the number of beats: after a series of electrical impulses, it starts to fade. With every contraction, we"re squeezing out the contractions. What if we take the heart of the frog out, and put another frog"s heart in: noticed the fluid stayed, has proven there is something in that solution that is inducing a change in heart responses. Seen in muscles and the heart: majority of synapses communicate via chemicals. Post-synaptic density (psd: anchor or the foundation for which receptors. Different types of synaptic connections: classic synapse, axo-somatic: axon and soma connection, axo-axonic: two axons connect, dendro dendritic: two dendrite connections. Modulation of activity: not the main source of input. Electrical signals are turned into chemical signals at synapses. Action potential does not exist in synapse.
