PSY397H5 Lecture Notes - Lecture 10: Growth Factor, Neurotransmitter, Synaptic Plasticity
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Block things and see what happens to the system, antagonists, lesion, block mechanisms, knockout genes, - block type experiment transcription process rna to protein will disrupt late phase. Block rna synthesis you also block aptitude. Target proteins are increasing ampa channels subunits are expressed and translated. Bdnf, brain derived neurotropic factors growth factor, also found in the adult, because the adult brain is still growing, growing new connections, synapses and remodeling of connections weakening, strengthening. Eph-tyrosine kinases, involved in growth processes, involved in synaptic plasticity and learning and memory. Mimic change and measure similar molecular change leads to late phase atrophy. L-ltp without tetanisation, create cells or organism in which creb acts without the need of phosphorylation, always active. Creb binds to camp response element binds to it and together with other factors the rna polymerase will make mrna. Ser 133 position, phosphorylated creb is activated. Match the particular sequence and attach to the dna.