BIOB51H3 Lecture Notes - Lecture 15: Gp41, Envelope Glycoprotein Gp120, Integrase
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Slide 2: squared and circles are pairs of species. Rectangles are lake-outlet stream and circles are lake-inlet stream. It affects us as hiv more than it would to some animals though. Slide 4: we"ll talk a(cid:271)out ho(cid:449) e(cid:448)olutio(cid:374)ary (cid:271)iology helps us to u(cid:374)dersta(cid:374)d a(cid:374)d fight aids. Slide 6: hiv happens world-wide, causes collapse of immune system and death from infections from things that normally. Infection of hiv leads to aids (cid:449)ould(cid:374)"t harm you if your immune system was doing well. Slide 8: majority of aids is in africa, also between heterosexuals, not just homosexuals, updated: between 3-5% of world-wide deaths. Inside capsules are integrase a(cid:374)d protease, a(cid:374)d rna ge(cid:374)o(cid:373)e. it"s a retro (cid:448)irus (rna dna host genome). Epitopes gp120 and gp41 are on surface of virus. Slide 10: exchange of body fluids are how it enters blood stream/lymphatic system, read slide. Slide 12: hiv infects cells with cd-4 surface proteins and ccr receptors (most strains).
