BIOC34H3 Lecture Notes - Lecture 8: Vascular Resistance, Blood Pressure, Series And Parallel Circuits
11 Mar 2018
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Document Summary
Jan. 31, 2018: 5% of 25 = 0. 91 l. Intrinsic (local) control of blood flow: tissues control blood flow via oxygen, Co2, chemicals and stretch, effecting smooth muscle relaxation and contraction: restricted blood flow occurs when smooth muscles constrict, allowing less blood to flow into organ and capillaries, -adrenoceptors control constriction while -adrenoceptors control dilation. Ischaemia is insufficient blood flow to meet metabolic demands: occurs when blood vessels are clogged or plaques have developed. Increased blood flow leads to increased o2 delivery: active hyperaemia is an increased blood flow in response to increased metabolic rate. Local co 2 changes: greater concentration of co2 means more metabolism is occurring and need increased blood flow to remove. Smooth muscle stretching: some smooth muscles are stretch sensitive, myogenic response is a direct response of vascular smooth muscles to changes in pressure. Increased pressure leads to smooth muscle contraction to protect small vessels from damage very important in brain.
