EESA10H3 Lecture Notes - Lecture 9: Chronic Toxicity, Rodent, Multiple Exposure
1 Apr 2017
School
Department
Course
Professor
Document Summary
Human health and environment lecture 9 toxicology. Transport: movement of contaminants within or between environmental media (soil, water, air) Fate: physical, chemical or biological transformation ns of contaminants in the environment (how they change) Fate and transport of chemicals is affected by their physical-chemical properties. How harmful a substance is depending on physical- chemical properties of the substance. Physical chemical properties: volatility electronegativity polarity solubility (water soluble toxins inorganic compounds or smaller molecules, fat soluble toxins (lipophilic tendency) oxidation state. Bioaccumulation- building up over time, in individual organisms. Biomagnification- building up overtime across the levels in a food chain. More lipophilic and more persistent less volatile and less water-soluble. Quantified as a half-life in air, water, or soil affected by environmental conditions. Toxicology the science of the effect of toxic substances and of their fate and transport in the body.
