EESA10H3 Lecture Notes - Lecture 10: Wingspread, Rodent, International Agency For Research On Cancer

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EESA10 Lecture 10 – Risk Assessment
Risk – possibility or probability of suffering harm from a hazard
Risk Assessment – A Regulatory Science
- WHY?
1. Must sometimes take action w/out further understanding of hazard
2. Risk assessment sets default procedures for bridging gaps in scientific understanding
3. Basic framework  evaluate exposure + toxicity; bring this info together to characterize a
health risk
- RISK ASSESSMENT – scientific process in estimating how much harm a particular hazard can
cause
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- BENEFITS – extracted from Natural Research Council
1. When agent suspected of causing diseases
2. Testing new chemical
3. Help rank contribution to overall risk
4. Help identify risks that are easily reduced/eliminated
5. Help clarified what is known + not known about situation
6. Can provide quantitative information for decision making
- APPLICATIONS:
1. Health Canada – regulations for foods + drugs
2. Canada Council of Ministers of the Environment
National Contaminated Sites Program
Canada-Wide Environmental Standards (CWES)
3. Ontario Ministry of Environment
Site-specific clean-up guidelines for contaminated soils
4. CEPA (Canadian Environmental Protection)
23 000 substances currently in use
Persistent, bioaccumulation, toxic
- STAGES:
1. Problem Definition
Purpose
Management goals
Policy context
Audience
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Document Summary

Risk possibility or probability of suffering harm from a hazard. Why: must sometimes take action w/out further understanding of hazard, risk assessment sets default procedures for bridging gaps in scientific understanding, basic framework evaluate exposure + toxicity; bring this info together to characterize a health risk. Risk assessment scientific process in estimating how much harm a particular hazard can cause. Applications: health canada regulations for foods + drugs, canada council of ministers of the environment. Canada-wide environmental standards (cwes: ontario ministry of environment. Site-specific clean-up guidelines for contaminated soils: cepa (canadian environmental protection) Contaminated soil, and/or air pollution and/or : receptor analysis. Organism, species/grps of species exposed to stressor. Length of exposure (life time, 20 yrs latency for cancer) Define routes of exposure (ingestion, inhalation, dermal) Determine rate of exposure from each route. Sensitive subpopulation (recent interest in children: pathways analyses. Determine environmental fate that results in exposure to receptor.

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