HLTB21H3 Lecture Notes - Lecture 6: Syphilis, Girolamo Fracastoro

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7 Nov 2011
Lecture 6
October 16, 2011
outbreak of a new epidemic in naples
-question: how did the disease get to naples in the first place?
girolamo fracastoro termed syphilis
-also known as morbus gallicus
it was named by the people of the groups that they didnʼt really like
italy and germany
related to who was not liked or what symptoms occurred as a result of it
theory 1:
-introduced to europe by chris columbus and his men
-signs of symptoms of syphilis in written records
-high virulence
theory 2:
-did not come into the old world from the new world from the crew
-existed in africa and Mediterranean and spread into europe
-arose from one origin and had different clinical patterns in certain conditions and
environmental factors
-non unitarian
-strains occured because of a result of mutations
-pinta, yals, endemic
-succession of mutation
john hunter: wanted to point to the similar origin of sexual diseases
-louʼs vinera
-single nature of louʼs vinera: wet form and dry form
-1 origin and 2 forms (ghonnerea and syphilis)
-g was the wet form
from the wet form, he developed the signs of the dry form
in 1830 it became known that it was 2 different diseases
john hunter didnʼt know that the person he injected himself with had g and s
rudolph: was spread through the blood
spiral shaped bacterium- trepenema paloden
Oslo Study 1891-1951: 2000 patients with primary or secondary syphilis
-based on symptoms
-followed over the period of time to uncover what happens to them naturally
tuskegee study- 1930: poor uneducated african american men that were never told
what they had
-even when there was a cure they were not aware of it
-told they had bad blood and were given free medical treatment and burials
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