PSYC62H3 Lecture Notes - Lecture 6: Nucleus Accumbens, Myocardial Infarction, Semantic Memory
Document Summary
Ethanol (etoh)/alcohol: metabolism of ethanol, gabaa receptors. Alcohol is a gabaa receptor +ive modulator. Reduces gabaa receptor levels/sensitivity: glutamate nmda receptors. Alcohol produces depressant effects by inhibiting excitatory glutamate nmda receptors. Chronic alcohol administration increases number of nmda receptors. What might this contribute to a higher risk for: serotonin receptors. Alcohol increases serotonin concentrations in the nucleus accumbens. May contribute to alcohol"s reinforcing effects: dose dependent effects. Alcohol"s pharmacological effects vary depending on alcohol"s [ ] in the body. Stroke: depressive effects on behaviour and cognition. Disinhibition (weakening of behavioural control) leads to: Loud outbursts and aggressive behaviour: subjective experience. Reduction in anxiety: adverse effects at high bac. Reversible drug-induced dementia characterized by stupor and anterograde amnesia. Inhibition of autonomic system functions: effects of chronic & heavy use. Ischemia (an inadequate supply of blood to an organ/part of the body, i. e. heart muscles), stroke, heart attack, cardiac arrhythmias.