BIO130H1 Lecture 4: Week 2 - Introduction to Nucleic Acids _ Proteins
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BIO130H1 Full Course Notes
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Week 2 - introduction to nucleic acids & proteins. Lecture outline: introduction to nucleic acids (finish from last week, molecular interactions, properties of nucleic acids, intro to proteins, amino acid structure, protein structure. 77-79 (from last week); 393-397; 33-42 (chemistry review); 50- 63; 70-72. Interactions between individual molecules usually mediated by noncovalent attractions. Not weakened by water, dynamic, attractions moving through the molecules all the time. Individually, very weak forces--but can pile up to generate strong bindings between molecules. 1) dna is synthesized from deoxyribonucleoside triphosphates, otherwise known as: dntps. 2) rna is synthesized from ribonucleoside triphosphates, or: ntps. 3) nucleotides are linked by: phosphodiester bonds. Oh on the 3" linked to a phosphate through to the 5" of the next nucleotide. 1) holds the dna double helix together. 2) a-t has 2 h bonds; g-c has 3 h bonds. 1. h bonds (represented by the dashed lines) A weak force, but can be accumulated.
