HMB265H1 Lecture Notes - Lecture 17: Exonuclease, Intron, Transposase
31 Jan 2018
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What characterizes: if a mutation is recessive, theres no haplo insufficiency. In the past, it was accepted that you cant have movement of certain parts of the genome. She noticed that theres 1 species of maize had frequent brakages at a particular chromosome. Maize chromosomes are large and wasily visualized by light microscopy. She postulated that there was movement of small segments of dna. mcclintoks: There are genes or controlling elements that can move around the chromosomes. She spectulated that ac and ds were transposable elemtns, they moved around. She also found that chromosomal breakage at the ds locus results in the loss in some cases of heterozygotes, results in the loss of some wild type alleles on everything on that side of the ds locus. All of the mitotic descendents of this cell will express a different phenotype from the rest of the cells that do(cid:374)"t ha(cid:448)e the (cid:271)(cid:396)eakage a(cid:374)d loss.
