PSL300H1 Lecture 1: Lecture One
Document Summary
Physiology is the science of how we stay alive and healthy. Core concepts for physiology: set 1 his. Systems: basis of what underlies physiology. Homeostasis is: homeo (gk homio = same, stasis (gk stasis = stand) Holding an internal environment constant despite changing conditions: the constancy of the internal environment claude bernard, 1880"s starting talking about regulation of internal workings of body, homeostasis , regulation of the internal environment walter b. cannon, 1929. How does body keep its internal environment constant? . Plasma and intracellular ion concentrations: extracellular fluid concentration of sodium has to be higher than the intracellular fluid concentration transport proteins work by using this gradient (sodium cotransporters) Very few proteins can get through this membrane so transport proteins are very important: intracellular fluid concentration of potassium = extracellular fluid concentration of sodium critical for neural function. Must maintain these concentrations: intracellular fluid concentration of chlorine is also less than extracellular fluid concentration.
