PSL300H1 Lecture Notes - Lecture 23: Blood Plasma, Transport Protein, Exocytosis
Document Summary
Activation of second messenger systems genes for transcription and translation. Modifications of existing proteins and induction of new protein synthesis. There are a lot of different stimuli in the external and internal environments of the cells: this stimulates the release of the hormone. Psl300 human physiology i v inside the cell, in order to release hormones, there can be changes in membrane potential: there can also be a change in free cytosolic ca2+ that can trigger hormone release. Atp-sensitive k+ channels on membrane: the atp blocks the channel, preventing the leakage of k+ from inside the cell. Hence, there is an accumulation of k+ inside the cell: this causes the cell to start depolarizing, the depolarization is sensed by the vg-ca2+ channels. There is an influx of ca2: vesicles stored in the cell start to undergo exocytosis, insulin is released.
