BIOL 312 Lecture Notes - Lecture 41: Henry Nicholas Ridley, Lethal Allele, Wolbachia
14 Dec 2017
School
Department
Course
Professor
Document Summary
Harmless until becoming a vector of a plant or animal pathogen. Switch from a native to an introduced plant. Resulting from agricultural practices (e. g. monoculture, high density) Produce a modification in the lab (e. g. a transgenic mosquito that suppresses growth of malaria) Introduce this modification into the field, such that it will spread throughout wild populations (tricky!) Release many sterile males that will interfere with successful reproduction of females in the wild. Suppresses but does not cause longterm genetic changes in wild populations. Release of insects carrying a dominant lethal allele (ridl) Mosquitoes genetically engineered to carry a gene that is only lethal in females. The action of the gene is suppressed by tetracycline (so that"s how the mosquitoes can be reared in the lab) males are released in the wild. Release of insects carrying a dominant lethal allele. Mosquitoes are genetically engineered to carry a gene only lethal in females.
