BIOL 465 Lecture Notes - Lecture 26: Phosphoinositide 3-Kinase, Natural Killer Cell, Cd19

• School: University of Victoria
• Department: Biology
• Course: BIOL 465
• Professor: Walter Patrick

Document Summary

Targeting macrophages sensitizes chronic lymphocytic leukemia to apoptosis and. Inhibits disease progression : cll is the prototype of chronic b cell tumors, and its development and progression depend on a complex network of cells including macrophages. Such as the importance of the monocyte/macrophage system and the roll of tams in cancer progression. Upon activation, the cytoplasmic tail of cd19 becomes phosphorylated, which leads to binding by src-family kinases and recruitment of pi-3 kinase. Cd20: is an activated glycosylated phosphoprotein expressed on the surface of all.