Class Notes (839,094)
Canada (511,185)
55-101 (38)
Habetler (38)
Lecture

Olfaction and Taste

1 Page
93 Views

Department
Biological Sciences
Course Code
55-101
Professor
Habetler

This preview shows half of the first page. Sign up to view the full page of the document.
Description
Outline of Lecture 68 (03-27 C; Ronnett) Olfaction and Taste I. Olfaction A) Anatomy - Primary olfactory neurons project through cribriform plate of ethmoid to the olfactory bulb - The olfactory brain is called the rhinencephalon - Olfactory epithelium is made of - sustentacular cells: supportive role - olfactory receptor neurons: capable of regenerating (unique in the CNS) - global basal cells: source of new ORNs B) Odorant recognition in the ORN - Detection: odorant binds receptor  G-protein  AC  cAMP  ion channel opening - Desensitization: 1) phosphorylation of receptor by GRKs or β-ARKs, OR 2) uncoupling of receptor from G-protein by arrestins C) Central processing of olfaction - Uniquely, there is no recognized olfactory topographic map, except for evidence that same areas of neuroepithelium project to same glomerulus in olfactory bulb - ORN  mitral or small tufted cells (in glomeruli)  olfactory tract 1) Anterior olfactory nucleus  contralateral olfactory bulb 2) Olfactory tubercle and pyriform cortex: conscious perception of odor 3) Amygdala and entorhinal cortex: affective response to odor D) Diseases of olfaction - There are a wide variety of ways hyposmia or anosmia results, e.g. from endocrine insufficiency,
More Less
Unlock Document

Only half of the first page are available for preview. Some parts have been intentionally blurred.

Unlock Document
You're Reading a Preview

Unlock to view full version

Unlock Document

Log In


OR

Join OneClass

Access over 10 million pages of study
documents for 1.3 million courses.

Sign up

Join to view


OR

By registering, I agree to the Terms and Privacy Policies
Already have an account?
Just a few more details

So we can recommend you notes for your school.

Reset Password

Please enter below the email address you registered with and we will send you a link to reset your password.

Add your courses

Get notes from the top students in your class.


Submit