CHEM 1100 Lecture Notes - Lecture 9: P53, Metastasis, Radiation Therapy

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Cells form masses (tumours: benign tumours : not cancerous. Cells don"t spread to other organs: malignant tumours, cells are able to spread, can break away from 1st site and enter bloodstream, form another tumour at 2nd site (metastasis) Cancer risk factors: environmental/lifestyle (~50%): smoking, diet, sun (causes mutation in cells, also some viruses cause cancer (e. g. cervical, human papilloma virus (hpv), genetic inheritance (2-3%): family history (genetic mutations- rare) e. g brca 1/2, p53. An estimated 173,000 new cases of cancer and 77,000 deaths will occur in canada in. On average, 487 canadians will be diagnosed with cancer everyday. On average, 205 canadians will die of cancer everyday. Cancer myths: childhood cancers (ages 0-14) are increasing. False: cancer incidence rate in children has been relatively constant since 1985, the cancer mortality rate continues to decline: cancer death rates are rising. False: almost all cancers show declining mortality rates when the aging population is factored in.

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