Anatomy and Cell Biology 4451F/G Lecture Notes - Lecture 21: Stroke, Growth Cone, Filopodia

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Helping the injured nervous system to repair itself. Prevention best strategy, so much harder to heal then prevent injury (helmets!, pa) Control inflammation (has not been so successful in stroke) Inflammation can lead to secondary injury, strategies that alter inflammatory response to injury. Improve blood flow (tpa: clot brusting drugs used a few hours after stroke, after ischemic stroke but not hemorrhagic, returning blood flow to stroke injured brain, one of the few things that really work if started early enough. Rehab: rehab to ppl with injuries to cns. It helps, (cid:271)ut (cid:449)e do(cid:374)"t k(cid:374)o(cid:449) (cid:272)ellular a(cid:374)d (cid:373)ole(cid:272)ular (cid:271)asis: probs has to do with enhancing re-wiring. Enhanced re-wiring: ns responds to injury by neuroplasticity ability of circuits to rewire to compensate for lost function. Lack of bilateral symmetry, half of brain missing. Surgical removal of this part due to epilepsy. Removed hemisphere of her brain huge wow.

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