Anatomy and Cell Biology 4451F/G Lecture Notes - Lecture 20: Neural Fold, Schwann Cell, Proteoglycan

• School: Western University
• Department: Anatomy and Cell Biology
• Course: Anatomy and Cell Biology 4451F/G
• Professor: All

Document Summary

Lecture 20: neurodevelopment: neuronal proliferation and migration, axon outgrowth, target innervation, synapse formation. Ectoderm starts to form neural plate that is organized by notochord. Eventually, these neural crests (ends of neural fold that are sticking up) start to meet each other. Neural crest fuses the plate to a neural tube. Neural tube then as it starts to close, will start cns. Neural tube closing, it closes last (at the two ends). Development of the pns (cid:862)neural (cid:272)rest(cid:863) (cid:272)ells (cid:373)igrate to for(cid:373) dorsal root sy(cid:373)patheti(cid:272), parasy(cid:373)patheti(cid:272) and enteric ganglia (also other tissue su(cid:272)h as (cid:272)artilage, (cid:271)o(cid:374)es, (cid:373)ela(cid:374)o(cid:272)ytes, ). Crest cells give rise to a huge variety of other cells depending on where along neural tube they are located. They give rise to melanocytes, dorsal root ganglia, Schwann cells, sympathetic ganglia, enteric ganglia and entire ganglia system. Also give rise to bone cells of the jaw and some parts of the skull.