Biochemistry 2280A Lecture Notes - Lecture 30: Homomeric, Polymerization, Treadmilling
11 May 2020
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Document Summary
Types of skeleton : rigid skeleton largely based on balance, can be fragile, contractile skeleton more robust. Actin filament structure: globular (g-actin) and once polymerised filamentous (f-actin) both forms, homomeric filaments all the subunits are the same (no dimers present, has a bound nucleotide atp. Myosin microfilament motor protein: there lots of variety in family, all have a motor domain that consumes atp, the rest of the structure depends on the purpose of the structure. ~2. 2um: z disc is a tethering point between two sarcomeres. Pushed forward by the polymerisation of actin, protrusion is the adhered to a new anchor point: stress fibres well aligned filaments, strong stable structures that apply tension across the whole cell not very mobile. Fibres contract, moving the body towards the new anchor point in a cyclic action: cortical actins surrounds the cell, provides structure within the membrane to help maintain integrity.
