Biology 2581B Lecture Notes - Lecture 18: User Friendly, Polyadenylation, Chromosome
22 Apr 2017
School
Department
Course
Professor
Document Summary
Genetic modifications: significant genetic alterations that are often not apparent or obvious given the primary dna sequence alone. Lecture 18: more on modifications & some bioinformatics. The amino acid sequence was derived using non-standard code. If we didn"t know that the mitochondrial genome for cox1 used a non-standard code, something very different would"ve been derived we would"ve predicted the wrong product. You can have the dna sequence, but if you don"t understand the modifications (editing), you"d be lost. We expect that if there"s a gene sequence, it gets transcribed, gives you an mrna. The dna sequence looks exactly like the mrna (identical: but this isn"t always true; can be completely wrong. Let"s look at the mitochondrial genome for this organism, call it gene a. Here, the ts all became us (not that weird), but something else came along and changed many of the cs to us as well: call this post-transcriptional editing (rna editing)
