Biology 2581B Lecture Notes - Lecture 18: Genbank, Genetic Drift, Horizontal Gene Transfer
24 Apr 2017
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Document Summary
Significant genetic alterations that are often not apparent or obvious given the primary dna sequence alone. Impact genetic information but may not know about them if just looking at the sequence. If know the sequence for a gene and but don"t know what code is used, could incorrectly interpret how the information is expressed. Cox 1 amino acid sequence (vertebrate mitochondrial code vs. standard genetic code) mitochondrial code. Aa sequence for the gene: translate the gene using the nonstandard vertebrate. If you didn"t know about the nonstandard codes and were asked to translate the gene for the amino acid sequence, would"ve had a different amino acid sequence. Genetic modifications are crucial and if you don"t know about them, they can push you: a sequence with many stop codons inserted throughout down another road. Modification that changes the underlying sequencing information. Thinking of genetics and central dogma, expect gene sequence to get transcribed to get an mrna.
