Biology 2581B Lecture Notes - Lecture 23: Dna Replication, Chromosome, Gene Duplication
13 Oct 2017
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Which way and which order genes are acting to develop an organism. How does one gene effect the expression of another, since there is a set order they work: you can follow expression patterns: compare things in different mutants and see the difference. Imaginal discs: from drosophila area that develops into wings. In the wild type we see an array of green, red and yellow: green: wingless protein, red: vestigial protein, yellow: both proteins are expressed, overlap zone. Potential protein interaction since one is necessary for the other. No vestigial expression anymore: no yellow where both proteins are expressed. Wingless affects where vestigial is expressed as the vestigial is not produced in many cells which it is found in the wt: vestigial expression depends on wingless being present in neighboring cells. Determining a pathway: we can analyze double mutants and compare to single mutant.
