Biology 1002B Lecture Notes - Lecture 2: Homochirality, Morning Sickness, Reducing Atmosphere
22 Jan 2017
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Life on earth started about 4 bya. What do you need: abiotic synthesis, heritable information, formation of cells, metabolism (energy). D-alanine and l-alanine: a(cid:373)e (cid:272)he(cid:373)i(cid:272)al a(cid:374)d physi(cid:272)al properties (cid:271)ut they do(cid:374)"t behave the same, e. g. thalidomide, had two enantiomers, one helped morning sickness and the other had birth defects in children (loss of limbs). Homochirality: essential to the evolution of life. All life: l amino acids, d sugars. Miller-urey racemic, equal amounts of both enantiomers (50% l amino acids, 50% d sugars. Heritable information, cells, metabolism: everything that is considered living uses the central dogma. Central dogma: dna rna protein: transcription requires enzymes, how do you get dna and rna without protein, rna was first to evolve: Structure and function (catalyst): genes are sequences of dna that encode for rna. 3% of genome trna used for the transfer in protein synthesis. rrna ribosomal rna.
