Biology 1002B Lecture Notes - Lecture 24: Simon Conway Morris, Pax6, Cone Cell
5 Apr 2017
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Supports simon conway morris: homology, opsins (class 2, crystallins (a group of proteins that makes the lens of the eye, crystallins are homologous to heat shock proteins (share a common ancestor) Eye structure: rod and cone cells (where opsin are found, cone cell-senses colour, millions of copies of rhodopsin, has mitochondria, nucleus. Biophysical basis of colour vision: can have 1 of 3 types of rhodopsin, short wave length rhodopsin (absorbs blue, medium wavelength rhodopsin (absorbs green, long wavelength(absorbs green/yellow) Trichromatic vision: due to the 3 types of rhodopsin, green, red, blue, all forms of rhodopsin have the same retinal. Amino acids in uence light absorption: speci c highly conserved amino acids(called residues, lysine at 226 is what binds the retinal, glutamic acid 113 stabilizes the lysine at 226. Location of opsin gene: lw and mw are close together, as evidence that they have arisen by gene duplication and diverged recently, sw is in a completely different chromosome.
