Biology 1002B Lecture Notes - Lecture 4: Volvox, Chlamydomonas, New York State Route 17K
16 Jan 2020
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Document Summary
Looking at genomic data and genomic sequence: glsa in volvox and chlamydomonas are homologous. Genome of chlamydomonas is very similar to that of volvox yet volvox is multicellular and division if labor and chlamydomonas is just one cell. Gene crucial to the development of multicellular properties in volvox. Glsa has unknown function in chlamydomonas: take the chlamydomonas gene and giving to volvox and you can rescue the mutant gene. Chlamydomonas gene so perfectly functional in volvox as well. Sequence alignment-you align the sequences to detect the similarity. Two ways that computer can do the alignment: global alignment-to align the sequences starting from one end and aligning all the way to other end, local alignment-working for small regions of high similarity. Computation is so much faster: national center for biotechnology information (ncbi) Repository of all genome, gene & protein data: wgs- whole genome sequence.
