Biology 1002B Lecture 20: Preparation + Lecture 20- DNA Technologies Genomics- Anuj Gupta

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Genomics the characterization of whole genomes, including their sq/structures, Indp for lecture 20 03/15/16 functions and evolution. Proteomics the study of proteome the complete set of proteins that can be produced by a single genome. Proteomics involves characterizing the structures and functions of all expressed proteins of an organism, and the interactions among proteins in the cell. Genomics has 3 main areas of study: genome sq determination and annotation. Obtaining the sqs (i. e. the bases) of complete genomes; analyzing it to locate. Pcg, noncoding rna genes and other important sqs: functional genomics (determining the functions of genes) Includes regulation of genes, which pcg codes for which protein, and how the protein functions: studying the evolution of genomes. Attempts to understand how genes (especially pcgs) originated and have changed overtime. All dna sqing methods have 5 steps in common: dna purification, dna fragmentation, amplification of fragments, sequencing each fragment; and, assembly of fragment sequences into genome sequences.

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